1- Now is this patient suitable for targeted EP mapping :substratemappint with EP suit " ?
2- If yes, what should do next ?
3- If not , what is your next step to "map" the V.Tach origin and to tell for surgeon about its localization ?
Substrate mapping
technique
Before to any planned
arrhythmia intervention , first must identify the target area for treatment .
Usually it’s done with either targeted EP mapping and/or systemic ECG
interpretation . using an essential technique of electrophysiologic substrate
mapping , a detailed schematic map of the heart is generated .
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This map is generated by
measuring endocadial voltage potentials at a variety of locations . In the
generated map , voltages greater than 1.5mV represent normal cardiac tissue and
appear purple ; voltages less tah 0.5 mV represent dead cardiac muscle and
appear red ; and voltages in between represent the borderline ischemic area and
are represented by a range of colors .
After substrate mapping
is completed the electrophysiologist and surgeon are able to carefully reviews
the generated projection and can specifically target the border zone areas of
potentially arrhythmogenic substrate for open intra-operative cryoablation at
the time of LVAD placement .
Note in figure 1 below the visualized EP mapping
catheter at the time of mapping in order to very specifically target the mapped arrhythmogenic substrate in real
time.
The main issue here is to
point , unfortunately , a hybrid suite is not available at this time and not
all patients are stable enough to tolerate transport to , and mapping in , the
EP suite . considering this practical issue , electrophysiologists devised a
compromise technique for targeting the locus of arrhythmia generating substrate
. In patients with hemodynamic instability who would not tolerate substrate
mapping in the EP suite , a systematic interpretation of 12-lead EKG results
capturing episodes of ventricular arrhythmia is performed . Systematic EKG analysis
of captured ventricular arrhythmia event is then used to localize the
arrhythmia origin to a anatomic area of the heart (i.e.LV lateral wall ) .
Using figure 2 . as an
example of sustained monomorphic VT , one first look at lead v1. If a left
bundle branch block (LBBB) is visible , the arrhythmia source comes from the RV
or septum, if a RBBB is visible , the arrhythmia is generated in the lV . one
cal then look at the direction of deflection of the QRS complex to more
specifically localize the arrhythmia focus . first , looking at the inferior
leads , II, III, avF , a positive wave localizes the focus to the anterior
aspect of the LV . Alternatively , a negative wave indicates posterior LV .
similiarly , the precordial leads are analyzed and a positive defelction in avR and v4 indicated an apex source , a
negative deflection points to the base of the ventricle . finally , lead I and
avL are analyzed , with a positive deflection indicating a septal soure , a
negative deflection pointing to a lateral wall source .
In this manner , the
focus of arrhythmogenic substrate can be localized to a specific area of the
heart that allows the surgeon to target this area intra-operatively with
cryoablation . for example , using strip below , the 12 lead ECG of captured
ventricular tachycardia can be used to localize the arrhythmia source to the
apical LV postero-septal wall . RBBB points to the LV , then inferior leads
points to the posterior surface , then precoardial leads indicate an apical
source , then I and avL point to the septum . Therefore , the LV postero-septal
wall close to the apex is likely the source .
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